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Total 12452 results found since Jan 2013.

Bipolar Risk Calculator Developed for At-Risk Youth
In a studypublished last week inJAMA Psychiatry, researchers reported the development of a calculator to predict the onset of a bipolar spectrum disorder (BPSD) in at-risk youth.BPSD was defined underDSM-IV criteria as bipolar I, bipolar II, cyclothymic disorder, or bipolar not otherwise specified.The BPSD risk calculator was found to be approximately 76% accurate, which is on par with a recently developed risk calculator fornew-onset psychosis as well as risk calculators used in other areas of medicine.“We recognize that replication of these findings is warranted before the risk calculator can be confidently used for cl...
Source: Psychiatr News - July 10, 2017 Category: Psychiatry Tags: bipolar disorder Bipolar risk calculator bipolar spectrum disorder CALS risk of bipolar disorder University of Utrecht Source Type: research

Pin-Size Battery Printed in 3-D
A new lithium-ion battery is one of the smallest ever made and the first battery to be created with a three-dimensional printer. Measuring less than a millimeter on each side, it fits comfortably on the head of pin and could potentially power tiny medical devices or miniature robots. [More]
Source: Scientific American - Official RSS Feed - June 20, 2013 Category: Science Tags: Technology,Energy Technology,Medical Technology,Energy Technology,Technology,Energy & Sustainability Source Type: research

Lower Urine Osmolality in Lithium Users Associated with Chronic Kidney Disease, Hypothyroidism, and Diabetes Mellitus: GSK-3β Inhibition as a Mechanism for Lithium-Associated Medical Illness?
Lithium is an essential mood disorder treatment. Unfortunately, lithium has been linked with several medical conditions, especially chronic kidney disease (CKD), although biological mechanisms are unknown. Glycogen synthase kinase3β inhibition (GSK3β), though, has been associated with low urine osmolality (UOsm) in lithium users and a broad variety of medical effects in other populations [1].
Source: Medical Hypotheses - March 6, 2015 Category: Biomedical Science Authors: Soham Rej, Marilyn Segal, Nancy C.P. Low, Istvan Mucsi, Christina Holcroft, Kenneth Shulman, Karl J. Looper Tags: Correspondence Source Type: research

In this correspondence, preliminary data in 100 lithium users found that urine osmolality correlated with chronic kidney disease, diabetes mellitus, and hypothyroidism. We hypothesize that GSK-3β inhibition is a potential mechanism for lithium-associated medical illness
Lithium is an essential mood disorder treatment. Unfortunately, lithium has been linked with several medical conditions, especially chronic kidney disease (CKD), although biological mechanisms are unknown. Glycogen synthase kinase3β inhibition (GSK3β), though, has been associated with low urine osmolality (UOsm) in lithium users and a broad variety of medical effects in other populations [1].
Source: Medical Hypotheses - March 6, 2015 Category: Biomedical Science Authors: Soham Rej, Marilyn Segal, Nancy C.P. Low, Istvan Mucsi, Christina Holcroft, Kenneth Shulman, Karl J. Looper Tags: Correspondence Source Type: research

FDA warns Abbott on St. Jude Medical plant in California
The FDA yesterday issued another warning letter about a St. Jude Medical (NYSE:STJ) plant in California, now owned by Abbott (NYSE:ABT), that makes cardiac rhythm management products. It’s at least the 2nd time the federal safety watchdog has flagged the plant in Sylmar, which makes defibrillators and the Merlin home cardiac monitor. In 2012 the FDA slapped St. Jude with a warning letter over problems with the manufacture of its Durata defibrillator leads; that letter was closed out in July 2014. Abbott paid $25 million earlier this year to acquire St. Jude. The FDA said inspections at the plant in February tur...
Source: Mass Device - April 13, 2017 Category: Medical Equipment Authors: Brad Perriello Tags: Food & Drug Administration (FDA) Wall Street Beat Abbott Cardiac Rhythm Management st-jude-medical Warning Letter Source Type: news

Novel Application Of 3D Printing Could Enable The Development Of Miniaturized Medical Implants
3D printing can now be used to print lithium-ion microbatteries the size of a grain of sand. The printed microbatteries could supply electricity to tiny devices in fields from medicine to communications, including many that have lingered on lab benches for lack of a battery small enough to fit the device, yet provide enough stored energy to power them. To make the microbatteries, a team based at Harvard University and the University of Illinois at Urbana-Champaign printed precisely interlaced stacks of tiny battery electrodes, each less than the width of a human hair...
Source: Health News from Medical News Today - June 21, 2013 Category: Consumer Health News Tags: Medical Devices / Diagnostics Source Type: news

Two UL Battery Safety Standards Are Now FDA Recognized Consensus Standards For Medical Devices
UL (Underwriters Laboratories), a global safety science leader, has announced that the U.S. Food and Drug Administration (FDA) has recognized two UL battery safety standards as consensus standards for medical devices incorporating lithium or nickel-based batteries.
Source: Medical Design Online News - July 24, 2014 Category: Medical Equipment Source Type: news

High-Performance Batteries for Medical Implants
These high-performance batteries are based on lithium-iodine or lithium-manganese dioxide. They feature high volumetric energy densities and low self-discharge. They’ve been specifically designed for use in medical implants.
Source: Medical Design Online Products - November 26, 2014 Category: Medical Equipment Source Type: news

Lithium Toxicity from the Addition of an ACE Inhibitor with an Unexpected Type I Brugada Pattern ECG: Case Files of the Medical Toxicology Fellowship at the University of California, San Diego.
PMID: 32297151 [PubMed - as supplied by publisher]
Source: Journal of Medical Toxicology - April 14, 2020 Category: Toxicology Authors: Schneir A, Masom CP Tags: J Med Toxicol Source Type: research

Why Not Pot? A Review of the Brain-based Risks of Cannabis
Conclusion Evaluating the potential harms of a commonly used drug—especially a complex substance like marijuana—is a challenging but vital task. Fully informed awareness of both the potential and proven benefits and the potential and proven harms of marijuana are necessary in order to have rational discussions with patients, teens, and decision makers regarding marijuana use. Based on a review of the current literature, we suggest the mnemonic DDUMB (dependence, driving, underachievement, mental illness, and “bad to worse”) as a tool that captures several of the more well-supported, brain-based risks associated wit...
Source: Innovations in Clinical Neuroscience - April 1, 2016 Category: Neuroscience Authors: ICN Online Editor Tags: Behavioral and Cognitive Neurology Child Adol Mental Disorders Cognition Current Issue Medical Issues Neurologic Systems and Symptoms Psychiatry Psychopharmacology Review Substance Use Disorders Cannabis dependence drug-related har Source Type: research

The Case Files: A Patient with Not-So-Benign Low Back Pain
By Chung, Arlene S. MD; Raukar, Neha P. MD   A 20-year-old man with a history of schizophrenia and polysubstance abuse presented to the ED complaining nonradiating, left-sided low back pain for one week. He denied any trauma, inciting event, intravenous drug use, tuberculosis exposure, or prior history of back pain or surgery. He also denied systemic symptoms such as fevers, sweats, abdominal pain, nausea, vomiting, leg pain, or difficulty walking.   He was taking risperidone and lithium, smoked a pack of cigarettes a day, did not drink alcohol, and occasionally used marijuana. Family history was negative for malignancy....
Source: The Case Files - June 12, 2014 Category: Emergency Medicine Tags: Blog Posts Source Type: research

Affective disorders: A question of continuing treatment during pregnancy (Review).
Authors: Trifu SC, Popescu A, Marian MA Abstract Fetal development, especially in the first trimester, has proven to be heavily influenced by external factors, such as chemical intake of medication. Chronic psychiatric treatment might interfere with the anatomical and physiological wellbeing of the fetus, because psychotropic medication proceeds past the placenta, into the amniotic fluid, and can enter breast milk. Hence some of the medications prescribed for mood disorders should be reconsidered during pregnancy, without sub-optimally treating when it is needed. A literature review is presented which systematicall...
Source: Experimental and Therapeutic Medicine - September 10, 2020 Category: General Medicine Tags: Exp Ther Med Source Type: research

Optimized osteogenesis of biological hydroxyapatite-based bone grafting materials by ion doping and osteoimmunomodulation
CONCLUSION: The doping of active inorganic ions is a reliable strategy to endow BHA-based biomaterials with osteoimmunomodulatory property and promote bone regeneration. Further studies are still in need to explore more ions and their effects in the crosstalk between the skeletal and immune systems.PMID:36245367 | DOI:10.3233/BME-221437
Source: Bio-Medical Materials and Engineering - October 17, 2022 Category: Materials Science Authors: Yihan Xing Xinyi Zhong Zhuofan Chen Quan Liu Source Type: research